相互作用
Ciprofloxacin + Sodium bicarbonate
重症度: 中等度
Ciprofloxacin and Sodium bicarbonate: moderate interaction.
最終更新日
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概要
Alkalinizing agents raise urinary pH and can reduce ciprofloxacin solubility, increasing the chance of crystalluria. Antacid effects may also slightly reduce absorption of oral ciprofloxacin.
この相互作用をわかりやすく説明すると
Ciprofloxacin and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Sodium bicarbonate belongs to Gastrointestinal Tract.
なぜ起こるのか
Decreased urinary solubility of ciprofloxacin in alkaline urine, with possible reduced gastric absorption.
対処法
Maintain good hydration and monitor renal function and urinalysis for crystalluria. Take ciprofloxacin at least 2 hours before the bicarbonate.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、CiprofloxacinとSodium bicarbonateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ciprofloxacinのその他の相互作用
Sodium bicarbonateのその他の相互作用
よくある質問
Can I take Ciprofloxacin with Sodium bicarbonate?
MediHelp rates the interaction as moderate. Ciprofloxacin and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alkalinizing agents raise urinary pH and can reduce ciprofloxacin solubility, increasing the chance of crystalluria. Antacid effects may also slightly reduce absorption of oral ciprofloxacin.
How serious is the interaction between Ciprofloxacin and Sodium bicarbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain good hydration and monitor renal function and urinalysis for crystalluria. Take ciprofloxacin at least 2 hours before the bicarbonate.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
