相互作用
Cisapride + Escitalopram
重症度: 併用禁忌
Cisapride and Escitalopram: contraindicated interaction.
最終更新日
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概要
Cisapride can cause dose-related torsades de pointes, and escitalopram also prolongs the QT interval in a dose-dependent fashion. The combination is contraindicated in the cisapride labelling.
この相互作用をわかりやすく説明すると
Cisapride and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cisapride belongs to Gastrointestinal Tract; Escitalopram belongs to Central Nervous System.
なぜ起こるのか
Additive QTc prolongation
対処法
Do not co-administer; use a prokinetic without QT effect or an alternative antidepressant.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CisaprideとEscitalopramの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cisaprideのその他の相互作用
Escitalopramのその他の相互作用
よくある質問
Can I take Cisapride with Escitalopram?
MediHelp rates the interaction as contraindicated. Cisapride and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cisapride can cause dose-related torsades de pointes, and escitalopram also prolongs the QT interval in a dose-dependent fashion. The combination is contraindicated in the cisapride labelling.
How serious is the interaction between Cisapride and Escitalopram?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; use a prokinetic without QT effect or an alternative antidepressant.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
