相互作用
Azithromycin + Cisapride
重症度: 併用禁忌
Azithromycin and Cisapride: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Both drugs can prolong the QT interval, and combined use increases the risk of torsades de pointes and sudden cardiac death. Cisapride labeling lists QT-prolonging drugs as contraindicated partners.
この相互作用をわかりやすく説明すると
Azithromycin and Cisapride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Azithromycin belongs to Anti Bacterial; Cisapride belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive QT prolongation through cardiac potassium channel blockade.
対処法
Do not co-administer; choose a non-QT-prolonging antibiotic or stop cisapride. Correct electrolytes and obtain an ECG if exposure has occurred.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzithromycinとCisaprideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cisaprideのその他の相互作用
Azithromycinのその他の相互作用
よくある質問
Can I take Azithromycin with Cisapride?
MediHelp rates the interaction as contraindicated. Azithromycin and Cisapride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs can prolong the QT interval, and combined use increases the risk of torsades de pointes and sudden cardiac death. Cisapride labeling lists QT-prolonging drugs as contraindicated partners.
How serious is the interaction between Azithromycin and Cisapride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; choose a non-QT-prolonging antibiotic or stop cisapride. Correct electrolytes and obtain an ECG if exposure has occurred.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Ceritinib. The full list is on the Cisapride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
