相互作用
Cyclosporine + Entecavir
重症度: 中等度
Cyclosporine and Entecavir: moderate interaction.
最終更新日
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概要
Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.
この相互作用をわかりやすく説明すると
Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Cyclosporine-related reduction in glomerular filtration may decrease renal clearance of entecavir.
対処法
Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CyclosporineとEntecavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Entecavirのその他の相互作用
よくある質問
Can I take Cyclosporine with Entecavir?
MediHelp rates the interaction as moderate. Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.
How serious is the interaction between Cyclosporine and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.
What other medicines interact with Entecavir?
MediHelp also lists interactions of Entecavir with, for example, Alogliptin-metformin, Canagliflozin-metformin, Cidofovir. The full list is on the Entecavir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
