相互作用
Deflazacort + Influenza virus vaccine quadrivalent intranasal
重症度: 併用禁忌
Deflazacort and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
最終更新日
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概要
The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
この相互作用をわかりやすく説明すると
Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression impairs clearance of live attenuated virus and the vaccine immune response.
対処法
Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DeflazacortとInfluenza virus vaccine quadrivalent intranasalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Deflazacortのその他の相互作用
よくある質問
Can I take Deflazacort with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
How serious is the interaction between Deflazacort and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
