相互作用
Deflazacort + Measles mumps and rubella vaccine live
重症度: 併用禁忌
Deflazacort and Measles mumps and rubella vaccine live: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.
この相互作用をわかりやすく説明すると
Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.
対処法
Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、DeflazacortとMeasles mumps and rubella vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Deflazacortのその他の相互作用
- Adenovirus types 4 and 7 live + Deflazacort 併用禁忌
- Bcg vaccine live + Deflazacort 併用禁忌
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine 併用禁忌
- Deflazacort + Measles mumps rubella and varicella vaccine live 併用禁忌
- Deflazacort + Measles vaccine 併用禁忌
よくある質問
Can I take Deflazacort with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.
How serious is the interaction between Deflazacort and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
