相互作用
Deflazacort + Measles vaccine
重症度: 併用禁忌
Deflazacort and Measles vaccine: contraindicated interaction.
最終更新日
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概要
Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
この相互作用をわかりやすく説明すると
Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts immunity.
対処法
Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、DeflazacortとMeasles vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Deflazacortのその他の相互作用
- Adenovirus types 4 and 7 live + Deflazacort 併用禁忌
- Bcg vaccine live + Deflazacort 併用禁忌
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine live 併用禁忌
- Deflazacort + Measles mumps rubella and varicella vaccine live 併用禁忌
よくある質問
Can I take Deflazacort with Measles vaccine?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
How serious is the interaction between Deflazacort and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。