相互作用
Delafloxacin + Didanosine
重症度: 中等度
Delafloxacin and Didanosine: moderate interaction.
最終更新日
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概要
Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
この相互作用をわかりやすく説明すると
Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Didanosine belongs to Anti Virals.
なぜ起こるのか
Chelation of delafloxacin by the polyvalent cations in buffered didanosine reduces absorption.
対処法
Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DelafloxacinとDidanosineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Delafloxacinのその他の相互作用
Didanosineのその他の相互作用
よくある質問
Can I take Delafloxacin with Didanosine?
MediHelp rates the interaction as moderate. Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
How serious is the interaction between Delafloxacin and Didanosine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
