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相互作用

Calcium + Delafloxacin

重症度: 中等度

Calcium and Delafloxacin: moderate interaction.

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概要

Calcium salts can bind oral delafloxacin in the gut, reducing its absorption and potentially causing treatment failure. The effect is well described for fluoroquinolones with polyvalent cations.

この相互作用をわかりやすく説明すると

Calcium and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium belongs to Gastrointestinal Tract; Delafloxacin belongs to Anti Bacterial.

エビデンスレベル: High

なぜ起こるのか

Chelation of delafloxacin by calcium cations in the gastrointestinal tract, reducing absorption.

対処法

Give oral delafloxacin at least 2 hours before or 6 hours after calcium products.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CalciumとDelafloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Calcium with Delafloxacin?

MediHelp rates the interaction as moderate. Calcium and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can bind oral delafloxacin in the gut, reducing its absorption and potentially causing treatment failure. The effect is well described for fluoroquinolones with polyvalent cations.

How serious is the interaction between Calcium and Delafloxacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after calcium products.

What other medicines interact with Calcium?

MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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