相互作用
Desipramine + Pentamidine
重症度: 併用禁忌
Desipramine and Pentamidine: contraindicated interaction.
最終更新日
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概要
Both drugs can prolong the QT interval, and pentamidine has been associated with torsades de pointes. The combination increases the risk of life-threatening arrhythmia.
この相互作用をわかりやすく説明すると
Desipramine and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Desipramine belongs to Central Nervous System; Pentamidine belongs to Anti Parasitic.
なぜ起こるのか
Additive QT prolongation.
対処法
Avoid the combination. If pentamidine is essential, consider withholding desipramine and monitor ECG and electrolytes.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DesipramineとPentamidineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Desipramineのその他の相互作用
Pentamidineのその他の相互作用
よくある質問
Can I take Desipramine with Pentamidine?
MediHelp rates the interaction as contraindicated. Desipramine and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs can prolong the QT interval, and pentamidine has been associated with torsades de pointes. The combination increases the risk of life-threatening arrhythmia.
How serious is the interaction between Desipramine and Pentamidine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. If pentamidine is essential, consider withholding desipramine and monitor ECG and electrolytes.
What other medicines interact with Desipramine?
MediHelp also lists interactions of Desipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Desipramine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
