相互作用
Diflunisal + Ketorolac
重症度: 併用禁忌
Diflunisal and Ketorolac: contraindicated interaction.
最終更新日
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概要
Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.
この相互作用をわかりやすく説明すると
Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Diflunisal belongs to Musculoskeletal; Ketorolac belongs to Musculoskeletal.
なぜ起こるのか
Additive NSAID toxicity (GI, renal, antiplatelet)
対処法
Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DiflunisalとKetorolacの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Diflunisalのその他の相互作用
Ketorolacのその他の相互作用
よくある質問
Can I take Diflunisal with Ketorolac?
MediHelp rates the interaction as contraindicated. Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.
How serious is the interaction between Diflunisal and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.
What other medicines interact with Diflunisal?
MediHelp also lists interactions of Diflunisal with, for example, Ketorolac intranasal, Acemetacin, Acetazolamide. The full list is on the Diflunisal page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
