相互作用
Digoxin + Lily of the valley
重症度: 併用禁忌
Digoxin and Lily of the valley: contraindicated interaction.
最終更新日
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概要
Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
この相互作用をわかりやすく説明すると
Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive Na+/K+-ATPase inhibition from plant cardiac glycosides and digoxin.
対処法
Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DigoxinとLily of the valleyの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Digoxinのその他の相互作用
よくある質問
Can I take Digoxin with Lily of the valley?
MediHelp rates the interaction as contraindicated. Digoxin and Lily of the valley are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lily of the valley (Convallaria majalis) contains cardiac glycosides such as convallatoxin. Combined with digoxin it causes additive glycoside effects and risk of digitalis toxicity with serious arrhythmias.
How serious is the interaction between Digoxin and Lily of the valley?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid lily of the valley preparations during digoxin therapy. If ingestion occurs, obtain ECG, potassium and digoxin level and manage as glycoside toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Squill, Adagrasib, Amiodarone. The full list is on the Digoxin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
