相互作用
Digoxin + Squill
重症度: 併用禁忌
Digoxin and Squill: contraindicated interaction.
最終更新日
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概要
Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
この相互作用をわかりやすく説明すると
Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive inhibition of Na+/K+-ATPase from the glycosides in squill and digoxin.
対処法
Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DigoxinとSquillの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Digoxinのその他の相互作用
よくある質問
Can I take Digoxin with Squill?
MediHelp rates the interaction as contraindicated. Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
How serious is the interaction between Digoxin and Squill?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Adagrasib, Amiodarone. The full list is on the Digoxin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
