相互作用
Dopamine + Selegiline transdermal
重症度: 併用禁忌
Dopamine and Selegiline transdermal: contraindicated interaction.
最終更新日
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概要
Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
この相互作用をわかりやすく説明すると
Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
MAO inhibition reduces dopamine breakdown and increases norepinephrine stores, amplifying sympathomimetic effects.
対処法
Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DopamineとSelegiline transdermalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dopamineのその他の相互作用
よくある質問
Can I take Dopamine with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
How serious is the interaction between Dopamine and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Amitriptyline. The full list is on the Dopamine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
