相互作用
Dihydroergotamine + Dopamine
重症度: 併用禁忌
Dihydroergotamine and Dopamine: contraindicated interaction.
最終更新日
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概要
Both agents cause vasoconstriction, and combined use can produce severe peripheral and cerebral vasospasm with marked hypertension. Ischemic complications have been described with ergot alkaloids and pressor agents.
この相互作用をわかりやすく説明すると
Dihydroergotamine and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Dopamine belongs to Cardiovascular.
なぜ起こるのか
Additive alpha-adrenergic and direct vascular smooth muscle vasoconstriction.
対処法
Avoid combining; use a non-ergot therapy for migraine in patients needing dopamine. If it occurs, monitor perfusion and blood pressure closely.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、DihydroergotamineとDopamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dopamineのその他の相互作用
Dihydroergotamineのその他の相互作用
よくある質問
Can I take Dihydroergotamine with Dopamine?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Dopamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents cause vasoconstriction, and combined use can produce severe peripheral and cerebral vasospasm with marked hypertension. Ischemic complications have been described with ergot alkaloids and pressor agents.
How serious is the interaction between Dihydroergotamine and Dopamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; use a non-ergot therapy for migraine in patients needing dopamine. If it occurs, monitor perfusion and blood pressure closely.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Selegiline transdermal, Amitriptyline. The full list is on the Dopamine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
