相互作用
Chlorpropamide + Dulaglutide
重症度: 中等度
Chlorpropamide and Dulaglutide: moderate interaction.
最終更新日
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概要
Dulaglutide increases glucose-dependent insulin secretion, and with a sulfonylurea it raises the risk of hypoglycemia. Chlorpropamide's long half-life can prolong any episodes.
この相互作用をわかりやすく説明すると
Chlorpropamide and Dulaglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpropamide belongs to Endocrine; Dulaglutide belongs to Endocrine.
なぜ起こるのか
Additive insulinotropic effects of GLP-1 receptor agonism and sulfonylurea-mediated insulin release.
対処法
Consider lowering the chlorpropamide dose when dulaglutide is started and monitor blood glucose.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ChlorpropamideとDulaglutideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Chlorpropamideのその他の相互作用
Dulaglutideのその他の相互作用
よくある質問
Can I take Chlorpropamide with Dulaglutide?
MediHelp rates the interaction as moderate. Chlorpropamide and Dulaglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dulaglutide increases glucose-dependent insulin secretion, and with a sulfonylurea it raises the risk of hypoglycemia. Chlorpropamide's long half-life can prolong any episodes.
How serious is the interaction between Chlorpropamide and Dulaglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the chlorpropamide dose when dulaglutide is started and monitor blood glucose.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
