相互作用
Eletriptan + Erythromycin lactobionate
重症度: 併用禁忌
Eletriptan and Erythromycin lactobionate: contraindicated interaction.
最終更新日
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概要
Intravenous erythromycin inhibits CYP3A4 and substantially increases eletriptan concentrations and half-life. The result may be exaggerated vasoconstriction with cardiovascular and hypertensive risk.
この相互作用をわかりやすく説明すると
Eletriptan and Erythromycin lactobionate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eletriptan belongs to Central Nervous System; Erythromycin lactobionate belongs to Anti Bacterial.
なぜ起こるのか
Inhibition of CYP3A4-mediated metabolism of eletriptan.
対処法
Do not use eletriptan within 72 hours of erythromycin. Consider another antibiotic such as azithromycin or another triptan.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、EletriptanとErythromycin lactobionateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eletriptanのその他の相互作用
Erythromycin lactobionateのその他の相互作用
よくある質問
Can I take Eletriptan with Erythromycin lactobionate?
MediHelp rates the interaction as contraindicated. Eletriptan and Erythromycin lactobionate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intravenous erythromycin inhibits CYP3A4 and substantially increases eletriptan concentrations and half-life. The result may be exaggerated vasoconstriction with cardiovascular and hypertensive risk.
How serious is the interaction between Eletriptan and Erythromycin lactobionate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use eletriptan within 72 hours of erythromycin. Consider another antibiotic such as azithromycin or another triptan.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
