相互作用
Erythromycin lactobionate + Flibanserin
重症度: 併用禁忌
Erythromycin lactobionate and Flibanserin: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Intravenous erythromycin inhibits CYP3A4 and can raise flibanserin concentrations. The result may be severe hypotension, syncope and sedation.
この相互作用をわかりやすく説明すると
Erythromycin lactobionate and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Erythromycin lactobionate belongs to Anti Bacterial; Flibanserin belongs to Genitourinary.
なぜ起こるのか
Inhibition of CYP3A4 reduces flibanserin clearance.
対処法
Avoid; hold flibanserin during erythromycin therapy or use a non-inhibiting antibiotic.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Erythromycin lactobionateとFlibanserinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Flibanserinのその他の相互作用
Erythromycin lactobionateのその他の相互作用
よくある質問
Can I take Erythromycin lactobionate with Flibanserin?
MediHelp rates the interaction as contraindicated. Erythromycin lactobionate and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intravenous erythromycin inhibits CYP3A4 and can raise flibanserin concentrations. The result may be severe hypotension, syncope and sedation.
How serious is the interaction between Erythromycin lactobionate and Flibanserin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; hold flibanserin during erythromycin therapy or use a non-inhibiting antibiotic.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
