相互作用
Eletriptan + Nelfinavir
重症度: 併用禁忌
Eletriptan and Nelfinavir: contraindicated interaction.
最終更新日
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概要
Nelfinavir strongly inhibits CYP3A4 and increases eletriptan plasma levels. Greater exposure increases the risk of vasoconstrictive cardiovascular adverse effects.
この相互作用をわかりやすく説明すると
Eletriptan and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eletriptan belongs to Central Nervous System; Nelfinavir belongs to Anti Virals.
なぜ起こるのか
Inhibition of CYP3A4-mediated metabolism of eletriptan.
対処法
Do not co-administer; avoid eletriptan for at least 72 hours after nelfinavir. Use an alternative triptan such as rizatriptan or sumatriptan.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EletriptanとNelfinavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eletriptanのその他の相互作用
Nelfinavirのその他の相互作用
よくある質問
Can I take Eletriptan with Nelfinavir?
MediHelp rates the interaction as contraindicated. Eletriptan and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Nelfinavir strongly inhibits CYP3A4 and increases eletriptan plasma levels. Greater exposure increases the risk of vasoconstrictive cardiovascular adverse effects.
How serious is the interaction between Eletriptan and Nelfinavir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; avoid eletriptan for at least 72 hours after nelfinavir. Use an alternative triptan such as rizatriptan or sumatriptan.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
