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相互作用

Flibanserin + Nelfinavir

重症度: 併用禁忌

Flibanserin and Nelfinavir: contraindicated interaction.

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概要

Nelfinavir inhibits CYP3A4 and can raise flibanserin concentrations. This increases the risk of severe hypotension, syncope and sedation.

この相互作用をわかりやすく説明すると

Flibanserin and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Flibanserin belongs to Genitourinary; Nelfinavir belongs to Anti Virals.

エビデンスレベル: Moderate

なぜ起こるのか

Inhibition of CYP3A4 reduces flibanserin metabolism.

対処法

Avoid the combination; do not use flibanserin with nelfinavir.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、FlibanserinとNelfinavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Flibanserin with Nelfinavir?

MediHelp rates the interaction as contraindicated. Flibanserin and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Nelfinavir inhibits CYP3A4 and can raise flibanserin concentrations. This increases the risk of severe hypotension, syncope and sedation.

How serious is the interaction between Flibanserin and Nelfinavir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; do not use flibanserin with nelfinavir.

What other medicines interact with Flibanserin?

MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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