相互作用
Ensitrelvir + Eplerenone
重症度: 併用禁忌
Ensitrelvir and Eplerenone: contraindicated interaction.
最終更新日
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概要
Ensitrelvir increases eplerenone exposure by inhibiting CYP3A. Higher levels raise the risk of hyperkalemia and related cardiac effects.
この相互作用をわかりやすく説明すると
Ensitrelvir and Eplerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ensitrelvir belongs to Anti Virals; Eplerenone belongs to Cardiovascular.
なぜ起こるのか
CYP3A inhibition reduces eplerenone clearance.
対処法
Do not use together; choose an alternative COVID-19 therapy or hold eplerenone only under clinician direction with potassium monitoring.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EnsitrelvirとEplerenoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ensitrelvirのその他の相互作用
Eplerenoneのその他の相互作用
よくある質問
Can I take Ensitrelvir with Eplerenone?
MediHelp rates the interaction as contraindicated. Ensitrelvir and Eplerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ensitrelvir increases eplerenone exposure by inhibiting CYP3A. Higher levels raise the risk of hyperkalemia and related cardiac effects.
How serious is the interaction between Ensitrelvir and Eplerenone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose an alternative COVID-19 therapy or hold eplerenone only under clinician direction with potassium monitoring.
What other medicines interact with Ensitrelvir?
MediHelp also lists interactions of Ensitrelvir with, for example, Apalutamide, Carbamazepine, Colchicine. The full list is on the Ensitrelvir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
