相互作用
Ensitrelvir + Enzalutamide
重症度: 併用禁忌
Ensitrelvir and Enzalutamide: contraindicated interaction.
最終更新日
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概要
Enzalutamide is a strong CYP3A inducer and is expected to considerably lower ensitrelvir exposure. Antiviral efficacy may be lost.
この相互作用をわかりやすく説明すると
Ensitrelvir and Enzalutamide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ensitrelvir belongs to Anti Virals; Enzalutamide belongs to Endocrine.
なぜ起こるのか
Enzalutamide induces CYP3A, accelerating ensitrelvir metabolism.
対処法
Do not co-administer; use an alternative COVID-19 agent not dependent on CYP3A exposure.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EnsitrelvirとEnzalutamideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ensitrelvirのその他の相互作用
Enzalutamideのその他の相互作用
よくある質問
Can I take Ensitrelvir with Enzalutamide?
MediHelp rates the interaction as contraindicated. Ensitrelvir and Enzalutamide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Enzalutamide is a strong CYP3A inducer and is expected to considerably lower ensitrelvir exposure. Antiviral efficacy may be lost.
How serious is the interaction between Ensitrelvir and Enzalutamide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; use an alternative COVID-19 agent not dependent on CYP3A exposure.
What other medicines interact with Ensitrelvir?
MediHelp also lists interactions of Ensitrelvir with, for example, Apalutamide, Carbamazepine, Colchicine. The full list is on the Ensitrelvir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
