相互作用
Ephedrine + Linezolid
重症度: 重大
Ephedrine and Linezolid: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Ephedrine releases norepinephrine and linezolid reduces its breakdown, so pressor responses can be exaggerated. Severe hypertension may occur.
この相互作用をわかりやすく説明すると
Ephedrine and Linezolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ephedrine belongs to Cardiovascular; Linezolid belongs to Anti Bacterial.
なぜ起こるのか
MAO inhibition enhances the indirect sympathomimetic effect of ephedrine.
対処法
Avoid if possible; if a vasopressor is needed, use a low dose of a direct agent with careful blood pressure titration. Monitor blood pressure continuously.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EphedrineとLinezolidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Linezolidのその他の相互作用
Ephedrineのその他の相互作用
よくある質問
Can I take Ephedrine with Linezolid?
MediHelp rates the interaction as major. Ephedrine and Linezolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ephedrine releases norepinephrine and linezolid reduces its breakdown, so pressor responses can be exaggerated. Severe hypertension may occur.
How serious is the interaction between Ephedrine and Linezolid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; if a vasopressor is needed, use a low dose of a direct agent with careful blood pressure titration. Monitor blood pressure continuously.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
