相互作用
Ethinylestradiol + Tranexamic acid
重症度: 併用禁忌
Ethinylestradiol and Tranexamic acid: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral tranexamic acid is antifibrinolytic and ethinylestradiol is prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
この相互作用をわかりやすく説明すると
Ethinylestradiol and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive prothrombotic effects of fibrinolysis inhibition and estrogen-induced increases in clotting factors.
対処法
Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EthinylestradiolとTranexamic acidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Tranexamic acidのその他の相互作用
よくある質問
Can I take Ethinylestradiol with Tranexamic acid?
MediHelp rates the interaction as contraindicated. Ethinylestradiol and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral tranexamic acid is antifibrinolytic and ethinylestradiol is prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
How serious is the interaction between Ethinylestradiol and Tranexamic acid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
