相互作用
Ethinyl estradiol-norgestimate + Tranexamic acid
重症度: 併用禁忌
Ethinyl estradiol-norgestimate and Tranexamic acid: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Combined hormonal contraceptives raise the risk of venous thromboembolism and tranexamic acid is antifibrinolytic, so together the thrombotic risk is increased. Oral tranexamic acid labeling contraindicates its use with combined hormonal contraception.
この相互作用をわかりやすく説明すると
Ethinyl estradiol-norgestimate and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ethinyl estradiol-norgestimate belongs to Endocrine; Tranexamic acid belongs to Cardiovascular.
なぜ起こるのか
Additive prothrombotic effects from estrogen-induced coagulation changes and antifibrinolysis.
対処法
Avoid coadministration; for heavy menstrual bleeding consider a non-hormonal or progestin-only alternative, or an alternative to tranexamic acid.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ethinyl estradiol-norgestimateとTranexamic acidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ethinyl estradiol-norgestimateのその他の相互作用
- Ethinyl estradiol-norgestimate + Fezolinetant 併用禁忌
- Ethinyl estradiol-norgestimate + Ombitasvir / paritaprevir / ritonavir and dasabuvir 併用禁忌
- Aminocaproic acid + Ethinyl estradiol-norgestimate 重大
- Amobarbital + Ethinyl estradiol-norgestimate 重大
- Anastrozole + Ethinyl estradiol-norgestimate 重大
- Apalutamide + Ethinyl estradiol-norgestimate 重大
Tranexamic acidのその他の相互作用
よくある質問
Can I take Ethinyl estradiol-norgestimate with Tranexamic acid?
MediHelp rates the interaction as contraindicated. Ethinyl estradiol-norgestimate and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combined hormonal contraceptives raise the risk of venous thromboembolism and tranexamic acid is antifibrinolytic, so together the thrombotic risk is increased. Oral tranexamic acid labeling contraindicates its use with combined hormonal contraception.
How serious is the interaction between Ethinyl estradiol-norgestimate and Tranexamic acid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid coadministration; for heavy menstrual bleeding consider a non-hormonal or progestin-only alternative, or an alternative to tranexamic acid.
What other medicines interact with Ethinyl estradiol-norgestimate?
MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Aminocaproic acid. The full list is on the Ethinyl estradiol-norgestimate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
