相互作用
Etretinate + Vitamin a
重症度: 重大
Etretinate and Vitamin a: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Etretinate is a retinoid, and vitamin A supplementation adds to retinoid toxicity, including hepatotoxicity, intracranial hypertension and mucocutaneous effects.
この相互作用をわかりやすく説明すると
Etretinate and Vitamin a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive retinoid pharmacodynamic effects leading to hypervitaminosis A-like toxicity.
対処法
Avoid vitamin A supplements during retinoid therapy; monitor liver tests and lipids.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EtretinateとVitamin aの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vitamin aのその他の相互作用
よくある質問
Can I take Etretinate with Vitamin a?
MediHelp rates the interaction as major. Etretinate and Vitamin a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etretinate is a retinoid, and vitamin A supplementation adds to retinoid toxicity, including hepatotoxicity, intracranial hypertension and mucocutaneous effects.
How serious is the interaction between Etretinate and Vitamin a?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vitamin A supplements during retinoid therapy; monitor liver tests and lipids.
What other medicines interact with Vitamin a?
MediHelp also lists interactions of Vitamin a with, for example, Acitretin, Isotretinoin, Palovarotene. The full list is on the Vitamin a page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
