相互作用
Bexarotene + Vitamin a
重症度: 中等度
Bexarotene and Vitamin a: moderate interaction.
最終更新日
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概要
Bexarotene is a retinoid, and adding vitamin A supplements can produce additive retinoid toxicity, including hypervitaminosis A symptoms, headache, liver injury and hypertriglyceridemia.
この相互作用をわかりやすく説明すると
Bexarotene and Vitamin a can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexarotene belongs to Oncology; Vitamin a belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive retinoid receptor-mediated pharmacodynamic effects.
対処法
Avoid vitamin A supplements above the recommended daily intake during bexarotene therapy; monitor lipids and liver tests.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BexaroteneとVitamin aの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vitamin aのその他の相互作用
Bexaroteneのその他の相互作用
よくある質問
Can I take Bexarotene with Vitamin a?
MediHelp rates the interaction as moderate. Bexarotene and Vitamin a can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexarotene is a retinoid, and adding vitamin A supplements can produce additive retinoid toxicity, including hypervitaminosis A symptoms, headache, liver injury and hypertriglyceridemia.
How serious is the interaction between Bexarotene and Vitamin a?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vitamin A supplements above the recommended daily intake during bexarotene therapy; monitor lipids and liver tests.
What other medicines interact with Vitamin a?
MediHelp also lists interactions of Vitamin a with, for example, Acitretin, Etretinate, Isotretinoin. The full list is on the Vitamin a page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
