相互作用
Acitretin + Vitamin a
重症度: 重大
Acitretin and Vitamin a: major interaction.
最終更新日
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概要
Acitretin is a retinoid, and taking vitamin A supplements with it adds to retinoid exposure. This can produce symptoms of hypervitaminosis A such as headache, dry skin and mucosa, liver enzyme elevation and raised intracranial pressure.
この相互作用をわかりやすく説明すると
Acitretin and Vitamin a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acitretin belongs to Miscellaneous; Vitamin a belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive retinoid pharmacological and toxic effects.
対処法
Avoid vitamin A supplements during acitretin therapy. Monitor for signs of hypervitaminosis A and liver tests.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AcitretinとVitamin aの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vitamin aのその他の相互作用
Acitretinのその他の相互作用
よくある質問
Can I take Acitretin with Vitamin a?
MediHelp rates the interaction as major. Acitretin and Vitamin a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Acitretin is a retinoid, and taking vitamin A supplements with it adds to retinoid exposure. This can produce symptoms of hypervitaminosis A such as headache, dry skin and mucosa, liver enzyme elevation and raised intracranial pressure.
How serious is the interaction between Acitretin and Vitamin a?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vitamin A supplements during acitretin therapy. Monitor for signs of hypervitaminosis A and liver tests.
What other medicines interact with Vitamin a?
MediHelp also lists interactions of Vitamin a with, for example, Etretinate, Isotretinoin, Palovarotene. The full list is on the Vitamin a page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
