相互作用
Ex vivo expanded autologous human corneal epithelial cells containing stem cells + Lidocaine
重症度: 重大
Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Topical lidocaine applied to the eye may be toxic to the cultured corneal epithelial cells and reduce the colony-forming capacity of the graft. This could impair engraftment and treatment success.
この相互作用をわかりやすく説明すると
Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ex vivo expanded autologous human corneal epithelial cells containing stem cells belongs to Miscellaneous; Lidocaine belongs to Cardiovascular.
なぜ起こるのか
Local anesthetic cytotoxicity to cultured epithelial stem cells reduces their viability.
対処法
Avoid topical lidocaine on the graft site or cell product. Follow the product labeling for the permitted anesthetic technique around the procedure.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ex vivo expanded autologous human corneal epithelial cells containing stem cellsとLidocaineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ex vivo expanded autologous human corneal epithelial cells containing stem cellsのその他の相互作用
Lidocaineのその他の相互作用
よくある質問
Can I take Ex vivo expanded autologous human corneal epithelial cells containing stem cells with Lidocaine?
MediHelp rates the interaction as major. Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Topical lidocaine applied to the eye may be toxic to the cultured corneal epithelial cells and reduce the colony-forming capacity of the graft. This could impair engraftment and treatment success.
How serious is the interaction between Ex vivo expanded autologous human corneal epithelial cells containing stem cells and Lidocaine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid topical lidocaine on the graft site or cell product. Follow the product labeling for the permitted anesthetic technique around the procedure.
What other medicines interact with Ex vivo expanded autologous human corneal epithelial cells containing stem cells?
MediHelp also lists interactions of Ex vivo expanded autologous human corneal epithelial cells containing stem cells with, for example, Epinephrine. The full list is on the Ex vivo expanded autologous human corneal epithelial cells containing stem cells page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
