相互作用
Insulin aspart-insulin aspart protamine + Rosiglitazone
重症度: 重大
Insulin aspart-insulin aspart protamine and Rosiglitazone: major interaction.
最終更新日
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概要
Rosiglitazone with insulin increases the risk of hypoglycemia, fluid retention, edema and heart failure. The combination is generally discouraged because of cardiovascular concerns.
この相互作用をわかりやすく説明すると
Insulin aspart-insulin aspart protamine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin aspart-insulin aspart protamine belongs to Endocrine; Rosiglitazone belongs to Endocrine.
なぜ起こるのか
Additive glucose lowering through PPAR-gamma insulin sensitization with insulin; both contribute to fluid retention.
対処法
Avoid in patients with heart failure or high cardiac risk. If used, monitor for fluid retention and glucose and reduce insulin as needed.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Insulin aspart-insulin aspart protamineとRosiglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin aspart-insulin aspart protamineのその他の相互作用
- Ethanol + Insulin aspart-insulin aspart protamine 重大
- Insulin aspart-insulin aspart protamine + Pentamidine 重大
- Insulin aspart-insulin aspart protamine + Pioglitazone 重大
- Acarbose + Insulin aspart-insulin aspart protamine 中等度
- Albiglutide + Insulin aspart-insulin aspart protamine 中等度
- Alogliptin + Insulin aspart-insulin aspart protamine 中等度
Rosiglitazoneのその他の相互作用
よくある質問
Can I take Insulin aspart-insulin aspart protamine with Rosiglitazone?
MediHelp rates the interaction as major. Insulin aspart-insulin aspart protamine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of hypoglycemia, fluid retention, edema and heart failure. The combination is generally discouraged because of cardiovascular concerns.
How serious is the interaction between Insulin aspart-insulin aspart protamine and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with heart failure or high cardiac risk. If used, monitor for fluid retention and glucose and reduce insulin as needed.
What other medicines interact with Insulin aspart-insulin aspart protamine?
MediHelp also lists interactions of Insulin aspart-insulin aspart protamine with, for example, Ethanol, Pentamidine, Pioglitazone. The full list is on the Insulin aspart-insulin aspart protamine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
