相互作用
Insulin degludec-insulin aspart + Rosiglitazone
重症度: 重大
Insulin degludec-insulin aspart and Rosiglitazone: major interaction.
最終更新日
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概要
Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
この相互作用をわかりやすく説明すると
Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec-insulin aspart belongs to Endocrine; Rosiglitazone belongs to Endocrine.
なぜ起こるのか
Rosiglitazone increases insulin sensitivity and causes fluid retention, adding to insulin effect and cardiac volume load.
対処法
Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Insulin degludec-insulin aspartとRosiglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin degludec-insulin aspartのその他の相互作用
Rosiglitazoneのその他の相互作用
よくある質問
Can I take Insulin degludec-insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
How serious is the interaction between Insulin degludec-insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
