相互作用
Insulin degludec / insulin aspart + Rosiglitazone
重症度: 重大
Insulin degludec / insulin aspart and Rosiglitazone: major interaction.
最終更新日
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概要
Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
この相互作用をわかりやすく説明すると
Insulin degludec / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive glucose-lowering effects, and combined sodium and fluid retention from thiazolidinedione and insulin.
対処法
Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Insulin degludec / insulin aspartとRosiglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Rosiglitazoneのその他の相互作用
よくある質問
Can I take Insulin degludec / insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
How serious is the interaction between Insulin degludec / insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
