相互作用
Insulin neutral human + Rosiglitazone
重症度: 重大
Insulin neutral human and Rosiglitazone: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Rosiglitazone with insulin increases the risk of fluid retention, edema, heart failure and hypoglycemia. The combination also carries a labeled cardiovascular concern, particularly in patients with cardiac risk.
この相互作用をわかりやすく説明すると
Insulin neutral human and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin neutral human belongs to Endocrine; Rosiglitazone belongs to Endocrine.
なぜ起こるのか
Additive improvement in insulin sensitivity plus PPAR-gamma-mediated sodium and fluid retention, which insulin can aggravate.
対処法
Avoid the combination in patients with heart failure or high cardiovascular risk; if used, reduce the insulin dose as needed and monitor weight, edema and cardiac symptoms.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Insulin neutral humanとRosiglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Insulin neutral humanのその他の相互作用
Rosiglitazoneのその他の相互作用
- Insulin aspart protamine / insulin aspart + Rosiglitazone 重大
- Insulin aspart-insulin aspart protamine + Rosiglitazone 重大
- Insulin aspart + Rosiglitazone 重大
- Insulin degludec / insulin aspart + Rosiglitazone 重大
- Insulin degludec-insulin aspart + Rosiglitazone 重大
- Insulin degludec-liraglutide + Rosiglitazone 重大
よくある質問
Can I take Insulin neutral human with Rosiglitazone?
MediHelp rates the interaction as major. Insulin neutral human and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of fluid retention, edema, heart failure and hypoglycemia. The combination also carries a labeled cardiovascular concern, particularly in patients with cardiac risk.
How serious is the interaction between Insulin neutral human and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in patients with heart failure or high cardiovascular risk; if used, reduce the insulin dose as needed and monitor weight, edema and cardiac symptoms.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
