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相互作用

Ketorolac + Meloxicam

重症度: 併用禁忌

Ketorolac and Meloxicam: contraindicated interaction.

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概要

Concurrent ketorolac and meloxicam increases the risk of gastrointestinal bleeding, kidney injury and cardiovascular events without extra pain relief. Ketorolac labeling contraindicates use with other NSAIDs.

この相互作用をわかりやすく説明すると

Ketorolac and Meloxicam are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ketorolac belongs to Musculoskeletal; Meloxicam belongs to Musculoskeletal.

エビデンスレベル: High

なぜ起こるのか

Additive cyclooxygenase inhibition affecting gastric mucosa, platelets and renal prostaglandins.

対処法

Do not use together; use only one NSAID and consider allowing for meloxicam's long half-life when switching.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、KetorolacとMeloxicamの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Ketorolac with Meloxicam?

MediHelp rates the interaction as contraindicated. Ketorolac and Meloxicam are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Concurrent ketorolac and meloxicam increases the risk of gastrointestinal bleeding, kidney injury and cardiovascular events without extra pain relief. Ketorolac labeling contraindicates use with other NSAIDs.

How serious is the interaction between Ketorolac and Meloxicam?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; use only one NSAID and consider allowing for meloxicam's long half-life when switching.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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