Drug interactions
Levothyroxine + Tiratricol
Severity: Major
Levothyroxine and Tiratricol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents are thyroid hormone analogues, so combining them adds thyromimetic activity and can cause thyrotoxic effects such as tachycardia and arrhythmia. Tiratricol also suppresses TSH and alters thyroid function tests.
What this interaction means in plain words
Levothyroxine and Tiratricol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levothyroxine belongs to Endocrine; Tiratricol belongs to Endocrine.
Why it happens
Additive thyroid hormone receptor agonism.
What to do
Avoid the combination unless specialist-directed. If used, monitor thyroid function tests and heart rate and adjust doses.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Tiratricol
- Calcium + Tiratricol Moderate
- Carbamazepine + Tiratricol Moderate
- Carbimazole + Tiratricol Moderate
- Charcoal + Tiratricol Moderate
- Chloroquine + Tiratricol Moderate
- Cholestyramine + Tiratricol Moderate
Other interactions of Levothyroxine
Frequently asked questions
Can I take Levothyroxine with Tiratricol?
MediHelp rates the interaction as major. Levothyroxine and Tiratricol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents are thyroid hormone analogues, so combining them adds thyromimetic activity and can cause thyrotoxic effects such as tachycardia and arrhythmia. Tiratricol also suppresses TSH and alters thyroid function tests.
How serious is the interaction between Levothyroxine and Tiratricol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination unless specialist-directed. If used, monitor thyroid function tests and heart rate and adjust doses.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Calcium, Carbamazepine, Carbimazole. The full list is on the Tiratricol page.
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