相互作用
Amobarbital + Levothyroxine
重症度: 中等度
Amobarbital and Levothyroxine: moderate interaction.
最終更新日
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概要
Barbiturates can speed up levothyroxine metabolism, which may raise dose requirements and lead to hypothyroidism in treated patients.
この相互作用をわかりやすく説明すると
Amobarbital and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Levothyroxine belongs to Endocrine.
なぜ起こるのか
Hepatic enzyme induction increases levothyroxine clearance.
対処法
Check TSH after starting or stopping amobarbital, and adjust the levothyroxine dose accordingly.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、AmobarbitalとLevothyroxineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amobarbitalのその他の相互作用
Levothyroxineのその他の相互作用
よくある質問
Can I take Amobarbital with Levothyroxine?
MediHelp rates the interaction as moderate. Amobarbital and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Barbiturates can speed up levothyroxine metabolism, which may raise dose requirements and lead to hypothyroidism in treated patients.
How serious is the interaction between Amobarbital and Levothyroxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check TSH after starting or stopping amobarbital, and adjust the levothyroxine dose accordingly.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
