相互作用
Magnesium + Sodium polystyrene sulfonate
重症度: 中等度
Magnesium and Sodium polystyrene sulfonate: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Sodium polystyrene sulfonate binds magnesium in the gut, so it may lower magnesium and cause hypomagnesemia with prolonged use. The legacy concern of raised magnesium levels is not well supported, and the mechanism is poorly characterized.
この相互作用をわかりやすく説明すると
Magnesium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
なぜ起こるのか
The resin exchanges sodium for cations including magnesium in the intestinal lumen, increasing fecal magnesium loss and also binding oral magnesium.
対処法
Monitor serum magnesium, potassium and calcium during repeated resin use. Separate oral magnesium from the resin by at least 3 hours and replace magnesium if low.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MagnesiumとSodium polystyrene sulfonateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Magnesiumのその他の相互作用
Sodium polystyrene sulfonateのその他の相互作用
よくある質問
Can I take Magnesium with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate binds magnesium in the gut, so it may lower magnesium and cause hypomagnesemia with prolonged use. The legacy concern of raised magnesium levels is not well supported, and the mechanism is poorly characterized.
How serious is the interaction between Magnesium and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, potassium and calcium during repeated resin use. Separate oral magnesium from the resin by at least 3 hours and replace magnesium if low.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
