医薬品リファレンス
Sodium polystyrene sulfonate
Sodium polystyrene sulfonate is a medicine in the class miscellaneous. It is used for hyperkalemia.
- 薬効分類: Miscellaneous
- 効能・効果: hyperkalemia
最終更新日
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要点
- 薬効分類
- Miscellaneous
- 一般的な剤形
- 経口懸濁液, 散剤
- 一般的な規格
- 15 g/60 ml, 454 g
- 既知の相互作用
- 11 (重大: 2 · 中等度: 7 · 軽度: 2)
- 商品名
- 2
- 国・市場
- 2
何に使われるか
作用のしくみ
Cation exchange resin, sodium ions partially released from polystyrene and replaced by potassium
成人の通常用量（添付文書の要約）
Hyperkalemia PO: 15 g once daily or q6-12hr
妊娠と授乳
- 妊娠
- Safe Not absorbed after oral or rectal use, so maternal use is not expected to expose the fetus (US label). UK label: no data, use only if the benefit outweighs the risk. Monitor potassium, calcium and magnesium, and watch for constipation.
- 授乳
- Safe Not absorbed by the mother, so it does not reach milk; no infant risk is expected (US label, LactMed). UK label: no data, use only if the benefit outweighs any risk. LactMed: no special precautions needed.
報告されている副作用
- Sodium retention, Fluid retention.
- Constipation
- Hypokalemia
- Hypomagnesemia
- Nausea and Vomiting
禁忌
- Hypersensitivity to polystyrene sulfonate resins
- Hypokalemia
- Obstructive bowel disease
注意が必要な方
- Best when used in non-life-threatening hyperkalemia
- Hypokalemia may occur monitor serum potassium frequently within each 24 hr period; ECG monitoring may be appropriate in some patients; cation exchange resins may also affect concentrations of other cations, including calcium and magnesium
- Use caution with dosage forms containing propylene glycol; large amounts are potentially toxic; associated with hyperosmolality, seizures, lactic acidosis, and respiratory depression
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (11)
- Meloxicam + Sodium polystyrene sulfonate Major
- Sodium polystyrene sulfonate + Sorbitol Major
- Calcium carbonate + Sodium polystyrene sulfonate Moderate
- Deflazacort + Sodium polystyrene sulfonate Moderate
- Levothyroxine + Sodium polystyrene sulfonate Moderate
- Lithium + Sodium polystyrene sulfonate Moderate
- Magnesium + Sodium polystyrene sulfonate Moderate
- Magnesium citrate + Sodium polystyrene sulfonate Moderate
- Magnesium hydroxide + Sodium polystyrene sulfonate Moderate
- Calcium + Sodium polystyrene sulfonate Minor
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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よくある質問
What is Sodium polystyrene sulfonate used for?
Sodium polystyrene sulfonate is a medicine in the class miscellaneous. It is used for Hyperkalemia.
What side effects have been reported with Sodium polystyrene sulfonate?
Sodium retention, Fluid retention., Constipation, Hypokalemia, Hypomagnesemia, Nausea and Vomiting.
Can Sodium polystyrene sulfonate be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not absorbed after oral or rectal use, so maternal use is not expected to expose the fetus (US label). UK label: no data, use only if the benefit outweighs the risk. Monitor potassium, calcium and magnesium, and watch for constipation. Breastfeeding: Safe. Not absorbed by the mother, so it does not reach milk; no infant risk is expected (US label, LactMed). UK label: no data, use only if the benefit outweighs any risk. LactMed: no special precautions needed.
What does Sodium polystyrene sulfonate interact with?
MediHelp lists 11 known interactions for Sodium polystyrene sulfonate. Major: 2 · Moderate: 7 · Minor: 2. The most serious include Meloxicam, Sorbitol, Calcium carbonate.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
