相互作用
Levothyroxine + Sodium polystyrene sulfonate
重症度: 中等度
Levothyroxine and Sodium polystyrene sulfonate: moderate interaction.
最終更新日
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概要
Sodium polystyrene sulfonate can bind oral levothyroxine in the gut and reduce its absorption. This may lower thyroid hormone exposure and lead to hypothyroidism over time.
この相互作用をわかりやすく説明すると
Levothyroxine and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Sodium polystyrene sulfonate belongs to Miscellaneous.
なぜ起こるのか
Binding of levothyroxine in the gastrointestinal tract by the resin reduces its absorption.
対処法
Give levothyroxine at least 3 hours apart from sodium polystyrene sulfonate. Monitor TSH and adjust the levothyroxine dose if needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、LevothyroxineとSodium polystyrene sulfonateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levothyroxineのその他の相互作用
Sodium polystyrene sulfonateのその他の相互作用
よくある質問
Can I take Levothyroxine with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Levothyroxine and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate can bind oral levothyroxine in the gut and reduce its absorption. This may lower thyroid hormone exposure and lead to hypothyroidism over time.
How serious is the interaction between Levothyroxine and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give levothyroxine at least 3 hours apart from sodium polystyrene sulfonate. Monitor TSH and adjust the levothyroxine dose if needed.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
