相互作用
Methylergonovine + Naratriptan
重症度: 併用禁忌
Methylergonovine and Naratriptan: contraindicated interaction.
最終更新日
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概要
Methylergonovine is a potent vasoconstrictor, and naratriptan adds further vasoconstriction. Prolonged vasospasm and ischemia may follow.
この相互作用をわかりやすく説明すると
Methylergonovine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive vasoconstriction via 5-HT1B/1D agonism and ergot adrenergic and serotonergic effects.
対処法
Do not give together; separate by at least 24 hours. Use a non-ergot uterotonic if bleeding control is needed.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MethylergonovineとNaratriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Naratriptanのその他の相互作用
よくある質問
Can I take Methylergonovine with Naratriptan?
MediHelp rates the interaction as contraindicated. Methylergonovine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylergonovine is a potent vasoconstrictor, and naratriptan adds further vasoconstriction. Prolonged vasospasm and ischemia may follow.
How serious is the interaction between Methylergonovine and Naratriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give together; separate by at least 24 hours. Use a non-ergot uterotonic if bleeding control is needed.
What other medicines interact with Naratriptan?
MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
