相互作用
Micafungin + Saccharomyces boulardii
重症度: 中等度
Micafungin and Saccharomyces boulardii: moderate interaction.
最終更新日
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概要
Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.
この相互作用をわかりやすく説明すると
Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Pharmacodynamic antagonism: antifungal activity against the live yeast probiotic.
対処法
Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MicafunginとSaccharomyces boulardiiの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Micafunginのその他の相互作用
よくある質問
Can I take Micafungin with Saccharomyces boulardii?
MediHelp rates the interaction as moderate. Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.
How serious is the interaction between Micafungin and Saccharomyces boulardii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Sirolimus, Avapritinib. The full list is on the Micafungin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
