相互作用
Isavuconazonium + Micafungin
重症度: 軽度
Isavuconazonium and Micafungin: minor interaction.
最終更新日
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概要
Micafungin is a weak CYP3A4 inhibitor, and isavuconazole is a CYP3A4 substrate, so a small rise in isavuconazole exposure is theoretically possible. This is unlikely to be clinically important, and the two antifungals are sometimes used together.
この相互作用をわかりやすく説明すると
Isavuconazonium and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Isavuconazonium belongs to Anti Fungals; Micafungin belongs to Anti Fungals.
なぜ起こるのか
Theoretical weak CYP3A4 inhibition by micafungin reducing isavuconazole clearance.
対処法
No empirical dose adjustment is needed; monitor for isavuconazole adverse effects such as liver enzyme elevation.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、IsavuconazoniumとMicafunginの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Micafunginのその他の相互作用
Isavuconazoniumのその他の相互作用
よくある質問
Can I take Isavuconazonium with Micafungin?
MediHelp rates the interaction as minor. Isavuconazonium and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Micafungin is a weak CYP3A4 inhibitor, and isavuconazole is a CYP3A4 substrate, so a small rise in isavuconazole exposure is theoretically possible. This is unlikely to be clinically important, and the two antifungals are sometimes used together.
How serious is the interaction between Isavuconazonium and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose adjustment is needed; monitor for isavuconazole adverse effects such as liver enzyme elevation.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
