相互作用
Avapritinib + Micafungin
重症度: 軽度
Avapritinib and Micafungin: minor interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Micafungin is a weak CYP3A4 inhibitor in vitro and may modestly raise avapritinib exposure. Clinically significant changes are not well documented, but higher avapritinib levels could increase adverse effects such as cognitive effects and bleeding.
この相互作用をわかりやすく説明すると
Avapritinib and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Avapritinib belongs to Oncology; Micafungin belongs to Anti Fungals.
なぜ起こるのか
Possible weak inhibition of CYP3A4-mediated avapritinib metabolism by micafungin.
対処法
No dose change is usually needed; monitor for avapritinib adverse effects such as cognitive changes, edema and bleeding when starting micafungin.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AvapritinibとMicafunginの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Micafunginのその他の相互作用
Avapritinibのその他の相互作用
よくある質問
Can I take Avapritinib with Micafungin?
MediHelp rates the interaction as minor. Avapritinib and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Micafungin is a weak CYP3A4 inhibitor in vitro and may modestly raise avapritinib exposure. Clinically significant changes are not well documented, but higher avapritinib levels could increase adverse effects such as cognitive effects and bleeding.
How serious is the interaction between Avapritinib and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for avapritinib adverse effects such as cognitive changes, edema and bleeding when starting micafungin.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
