Interações medicamentosas
Abacavir + Methadone
Gravidade: Leve
Abacavir and Methadone: minor interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
O que esta interação significa em palavras simples
Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Abacavir belongs to Anti Virals; Methadone belongs to Musculoskeletal.
Por que acontece
Possible modest increase in methadone clearance; the exact mechanism is not established.
O que fazer
Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
O que perguntar ao farmacêutico
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Abacavir e Methadone, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Outras interações de Methadone
- Alvimopan + Methadone Contraindicada
- Calcium / magnesium / potassium / sodium oxybates + Methadone Contraindicada
- Droperidol + Methadone Contraindicada
- Ibutilide + Methadone Contraindicada
- Isocarboxazid + Methadone Contraindicada
- Lefamulin + Methadone Contraindicada
Outras interações de Abacavir
- Abacavir + Ribavirin Moderada
- Abacavir + Efavirenz Leve
- Abacavir + Emtricitabine Leve
- Abacavir + Ganciclovir Leve
- Abacavir + Nevirapine Leve
- Abacavir + Valganciclovir Leve
Perguntas frequentes
Can I take Abacavir with Methadone?
MediHelp rates the interaction as minor. Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
How serious is the interaction between Abacavir and Methadone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
What other medicines interact with Methadone?
MediHelp also lists interactions of Methadone with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Droperidol. The full list is on the Methadone page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
