Interações medicamentosas
Acetylcysteine + Nitroglycerin
Gravidade: Moderada
Acetylcysteine and Nitroglycerin: moderate interaction.
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Resumo
Acetylcysteine may potentiate the vasodilating effect of nitroglycerin, with possible hypotension and headache. The effect is mainly described with intravenous nitroglycerin.
O que esta interação significa em palavras simples
Acetylcysteine and Nitroglycerin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylcysteine belongs to Respiratory; Nitroglycerin belongs to Cardiovascular.
Por que acontece
Acetylcysteine supplies thiol groups that may enhance nitroglycerin bioactivation and nitric oxide-mediated vasodilation.
O que fazer
Monitor blood pressure and headache when acetylcysteine is given with intravenous nitroglycerin, and reduce the nitroglycerin infusion rate if hypotension occurs.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Acetylcysteine
Outras interações de Nitroglycerin
- Avanafil + Nitroglycerin Contraindicada
- Nitroglycerin + Riociguat Contraindicada
- Nitroglycerin + Sildenafil Contraindicada
- Nitroglycerin + Tadalafil Contraindicada
- Nitroglycerin + Vardenafil Contraindicada
- Dihydroergotamine intranasal + Nitroglycerin Grave
Perguntas frequentes
Can I take Acetylcysteine with Nitroglycerin?
MediHelp rates the interaction as moderate. Acetylcysteine and Nitroglycerin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Acetylcysteine may potentiate the vasodilating effect of nitroglycerin, with possible hypotension and headache. The effect is mainly described with intravenous nitroglycerin.
How serious is the interaction between Acetylcysteine and Nitroglycerin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and headache when acetylcysteine is given with intravenous nitroglycerin, and reduce the nitroglycerin infusion rate if hypotension occurs.
What other medicines interact with Acetylcysteine?
MediHelp also lists interactions of Acetylcysteine with, for example, Nitroglycerin po, Nitroglycerin rectal, Nitroglycerin sublingual. The full list is on the Acetylcysteine page.
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