Interações medicamentosas
Acetylsalicylic acid + Mesalamine
Gravidade: Moderada
Acetylsalicylic acid and Mesalamine: moderate interaction.
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Resumo
Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
O que esta interação significa em palavras simples
Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Mesalamine belongs to Gastrointestinal Tract.
Por que acontece
Additive effects on renal prostaglandin-dependent perfusion and possible direct tubulointerstitial toxicity of salicylates.
O que fazer
Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicada
- Acetylsalicylic acid + Ketorolac intranasal Contraindicada
- Abciximab + Acetylsalicylic acid Grave
- Acemetacin + Acetylsalicylic acid Grave
- Acetazolamide + Acetylsalicylic acid Grave
- Acetylsalicylic acid + Alteplase Grave
Outras interações de Mesalamine
Perguntas frequentes
Can I take Acetylsalicylic acid with Mesalamine?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
How serious is the interaction between Acetylsalicylic acid and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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