Interações medicamentosas
Dihydroergotamine + Ergotamine
Gravidade: Contraindicada
Dihydroergotamine and Ergotamine: contraindicated interaction.
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Resumo
Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.
O que esta interação significa em palavras simples
Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
Por que acontece
Additive vasoconstriction from ergot alkaloid agonism at serotonin and adrenergic receptors.
O que fazer
Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Ergotamine
- Almotriptan + Ergotamine Contraindicada
- Atazanavir + Ergotamine Contraindicada
- Clarithromycin + Ergotamine Contraindicada
- Cobicistat + Ergotamine Contraindicada
- Darunavir + Ergotamine Contraindicada
- Dihydroergotamine intranasal + Ergotamine Contraindicada
Outras interações de Dihydroergotamine
- Almotriptan + Dihydroergotamine Contraindicada
- Clarithromycin + Dihydroergotamine Contraindicada
- Dihydroergotamine + Dopamine Contraindicada
- Dihydroergotamine + Dronedarone Contraindicada
- Dihydroergotamine + Efavirenz Contraindicada
- Dihydroergotamine + Eletriptan Contraindicada
Perguntas frequentes
Can I take Dihydroergotamine with Ergotamine?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.
How serious is the interaction between Dihydroergotamine and Ergotamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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