Interações medicamentosas
Amlodipine-hydrochlorothiazide-valsartan + Vitamin d
Gravidade: Moderada
Amlodipine-hydrochlorothiazide-valsartan and Vitamin d: moderate interaction.
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Resumo
Thiazide diuretics reduce renal calcium excretion, and vitamin D increases intestinal calcium absorption. Together they may cause hypercalcemia, particularly with high-dose vitamin D or in patients with renal impairment.
O que esta interação significa em palavras simples
Amlodipine-hydrochlorothiazide-valsartan and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Vitamin d belongs to Gastrointestinal Tract.
Por que acontece
Reduced urinary calcium excretion by hydrochlorothiazide combined with increased calcium absorption from vitamin D.
O que fazer
Monitor serum calcium periodically, especially with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia occurs.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicada
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicada
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Grave
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Grave
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Grave
Outras interações de Vitamin d
- Aluminum hydroxide + Vitamin d Grave
- Amlodipine-olmesartan-hydrochlorothiazide + Vitamin d Moderada
- Atenolol-chlorthalidone + Vitamin d Moderada
- Calcium acetate + Vitamin d Moderada
- Calcium carbonate + Vitamin d Moderada
- Calcium chloride + Vitamin d Moderada
Perguntas frequentes
Can I take Amlodipine-hydrochlorothiazide-valsartan with Vitamin d?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics reduce renal calcium excretion, and vitamin D increases intestinal calcium absorption. Together they may cause hypercalcemia, particularly with high-dose vitamin D or in patients with renal impairment.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Vitamin d?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically, especially with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia occurs.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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