Interações medicamentosas
Atenolol-chlorthalidone + Vitamin d
Gravidade: Moderada
Atenolol-chlorthalidone and Vitamin d: moderate interaction.
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Resumo
Thiazide-type diuretics such as chlorthalidone reduce urinary calcium excretion. Combined with vitamin D, which enhances calcium absorption, this can cause hypercalcemia, particularly with high doses or in renal impairment.
O que esta interação significa em palavras simples
Atenolol-chlorthalidone and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Vitamin d belongs to Gastrointestinal Tract.
Por que acontece
Reduced renal calcium excretion from the thiazide plus increased intestinal calcium absorption from vitamin D.
O que fazer
Monitor serum calcium and renal function periodically, especially when doses are high or calcium supplements are also used. Reduce the vitamin D or calcium dose if hypercalcemia develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Atenolol-chlorthalidone
Outras interações de Vitamin d
Perguntas frequentes
Can I take Atenolol-chlorthalidone with Vitamin d?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide-type diuretics such as chlorthalidone reduce urinary calcium excretion. Combined with vitamin D, which enhances calcium absorption, this can cause hypercalcemia, particularly with high doses or in renal impairment.
How serious is the interaction between Atenolol-chlorthalidone and Vitamin d?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and renal function periodically, especially when doses are high or calcium supplements are also used. Reduce the vitamin D or calcium dose if hypercalcemia develops.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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