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Interações medicamentosas

Amlodipine-benazepril + Amphotericin b liposomal

Gravidade: Moderada

Amlodipine-benazepril and Amphotericin b liposomal: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Amphotericin B can cause infusion-related hypotension and nephrotoxicity. Antihypertensives like amlodipine and benazepril may add to hypotension, and ACE inhibitors may worsen renal function in volume-depleted patients.

O que esta interação significa em palavras simples

Amlodipine-benazepril and Amphotericin b liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amlodipine-benazepril belongs to Cardiovascular; Amphotericin b liposomal belongs to Anti Fungals.

Nível de evidência: Low

Por que acontece

Additive hypotensive effects, with amphotericin renal toxicity compounding ACE inhibitor effects on glomerular filtration.

O que fazer

Monitor blood pressure during infusions and check renal function and potassium regularly. Consider holding benazepril if renal function declines.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Amlodipine-benazepril with Amphotericin b liposomal?

MediHelp rates the interaction as moderate. Amlodipine-benazepril and Amphotericin b liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause infusion-related hypotension and nephrotoxicity. Antihypertensives like amlodipine and benazepril may add to hypotension, and ACE inhibitors may worsen renal function in volume-depleted patients.

How serious is the interaction between Amlodipine-benazepril and Amphotericin b liposomal?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during infusions and check renal function and potassium regularly. Consider holding benazepril if renal function declines.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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